产品货号：
Z26646
中文名称：
SKIL抗体
英文名称：
Anti-SKIL Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SKIL Antibody |
| 指标别名 | SKI like oncogene;Ski like protein;Ski related oncogene;Ski related protein;SKIL;SNO;SnoA;SnoI;SnoN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SKIL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SnoN antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SnoN.The immunogen is located within the first 50 amino acids of SnoN. |
| 计算分子量 | 77kDa |
| 成分 | SnoN Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SnoN Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis.This signaling is negatively regulated by Ski,the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells,and the related protein SnoN.Like Ski,SnoN functions by binding to the Smad proteins and preventing their phosphorylation,thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes.SnoN is located primarily in the nucleus in cancer tissues or cells,but in the cytoplasm in normal tissues or primary epithelial cells.There are at least four alternately spliced isoforms of SnoN;SnoN antibody will recognize all isoforms (SnoN,SnoN2,SnoI,and SnoA). |
| Uniprot ID | P12757 |
| 基因名全称 | SKI-like oncogene |
| 蛋白名全称 | SKI-like oncogene |
| 推荐稀释比 | SnoN antibody can be used for detection of SnoN by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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